Sharon Osbourne has double mastectomy: magazine
















LONDON (Reuters) – British celebrity Sharon Osbourne has had a double mastectomy after discovering she was carrying a gene that increased the risk of her developing breast cancer, she told Hello! magazine in an interview published on Monday.


Osbourne, 60, told the publication that the decision was a “no-brainer” in the end.













“As soon as I found out I had the breast cancer gene, I thought: ‘The odds are not in my favor’,” she said in remarks that also ran in the Daily Mirror tabloid.


“I’ve had cancer before and I didn’t want to live under that cloud: I decided to just take everything off, and had a double mastectomy.”


Osbourne, who put the eccentric life of her family on view in the reality TV series “The Osbournes”, said she did not want to spend the rest of her life with “that shadow hanging over me.


“I want to be around for a long time and be a grandmother to Pearl,” she added, referring to her son Jack’s first child.


“I didn’t even think of my breasts in a nostalgic way, I just wanted to be able to live my life without that fear all the time. It’s not ‘pity me’, it’s a decision I made that’s got rid of this weight that I was carrying around.”


Osbourne raised her profile by appearing as a judge on successful talent shows “The X Factor” and “America’s Got Talent”. She is married to heavy metal singer Ozzy Osbourne.


Her London publicist referred Reuters to the interview which ran in Hello! and the Daily Mirror when asked to confirm the news.


(Reporting by Mike Collett-White, editing by Paul Casciato)


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Hurricane Sandy Hints At The Perils Of Global Catastrophe
















It takes a lot to bump the United States election out of the national spotlight one week before election day. Hurricane Sandy was that big, a direct blow to the most heavily populated region of the country. But all the attention going to the northeastern U.S. has a sad consequence: we’re overlooking the devastation Sandy caused in Haiti. This situation offers an ominous warning of what could happen if catastrophe were to affect the entire planet.

Candlelit bar in Greenwich Village, Manhattan. Photo credit: Seth Baum

This story is very personal for me. I live in New York City, and I do research on global catastrophes. While my neighborhood (Harlem) never lost electricity, this past Thursday and Friday I ventured to the area of Lower Manhattan that did. The area was much quieter than normal – clearly many people had left town. Of the remaining local residents, some reported enjoying the simpler life of “camping at home” and candlelit bars, while others were sick of it and wanted things back to normal. I even saw one woman frantically trying to care for an elderly neighbor who had run out of food and lacked the strength to go outside without her building’s elevator. This is a difficult situation, but as I know from my research, it could have been a lot worse. Meanwhile in Haiti, things may be worse. It seems sadly inevitable that we have the worst storm to hit the northeastern U.S. in a very long time, and it is disaster-stricken Haiti that may have been hit the hardest. At least 60 Haitians have died from Sandy. The U.S. has more deaths, but these are spread across a much larger affected population. Meanwhile Haiti may now have 200,000 homeless from Sandy, many of whom were still living in makeshift homes built following the 2010 earthquake. Its cholera outbreak could be worsened by the floods. But most worrisome is the large loss of crops. Haiti has an agriculture-oriented economy. The crop damage is prompting concerns about food shortages. For all the destruction in the U.S., it’s not at risk of running out of food.

Flooding in Haiti caused by Hurricane Sandy. Photo credit: Chimen Lakay, IOM Haiti












Despite the dire situation in Haiti, U.S. aid efforts are concentrated on the U.S. side of the storm. A giant benefit concert was held for the American Red Cross. Other domestic aid charities have also reported a spike in donations, whereas international charities report receiving much less. It is quite reasonable for the U.S. to focus on helping its own country, but it is nonetheless unfortunate that this focus could leave Haitians to suffer. Haiti should get the aid it needs. The U.S. should even be able to help. Yes, we have our own recovery to attend to, but we are a large and wealthy country, most of which was not hit by the storm. Even if the U.S. does not contribute, the rest of the world could, just as it did following the 2010 Haiti earthquake and every other major disaster of recent years. The propensity for countries to help each other out in times of great need – even when those countries are otherwise at odds – is among the most uplifting features of the international system. But a global catastrophe could thwart the international assistance paradigm. Just as the U.S. is now less able to aid Haiti, a global-scale event could leave each country devastated and with nowhere to turn for help. Each country would have to attempt recovery on its own. Each region within a country may be left to its own devices. Without external assistance, the challenge of recovery would be much more difficult. No hurricane, however large, will ever cause so great of a global catastrophe. But other events could [1]. Some come from nature, including supervolcano eruptions and large asteroid impacts. But these events are relatively rare, happening no more often than once every 50,000 years. The most urgent come from human activity, including nuclear war and pandemics. Pandemics could come from nature or from bioengineering, but either type of pathogen would be spread by human trade and travel. The worst-case nuclear war and pandemic scenarios are plenty bad enough to prevent international and inter-regional aid. Other processes like climate change and biodiversity loss can cause global disruptions and help trigger global catastrophes. In the event of a global catastrophe, each region could be left on its own. There would be no benefit concert, no international aid. If a region runs out of food supplies, its residents simply start dying. Rural Haiti may actually fare better than urban New York City, since Haitians are able to grow their own food. New York City without food supplies is a scary thought. A societal breakdown and collapse of law and order is possible, though also not inevitable. Research on the effects of resource scarcities on conflict and violence paints a mixed picture: sometimes scarcities bring more conflict, but not always [2]. Either way, this sort of global catastrophe poses challenges that go far beyond those of Hurricane Sandy. Fortunately, we do have tools we can use to rise to the challenges of global catastrophe. Building local self-sufficiency can be crucial if external aid becomes unavailable. Preparations like stockpiling food and water help people endure catastrophes of all sizes. Research on specific threats and cross-cutting issues can clarify what we’re up against and point to smarter opportunities to both prevent global catastrophes and recover from them if they occur. And experience with local catastrophes can often be extrapolated to the global scale, as is the case with Hurricane Sandy. As the recovery from Sandy proceeds, we should work towards building society’s resilience to both local and global catastrophes. References: [1] Bostrom, Nick and Milan ?irkovi?, 2008. Global Catastrophic Risks. Oxford: Oxford University Press. [2] Nord?s, Ragnhild and Nils Petter Gleditsch, 2007. Climate change and conflict. Political Geography, vol. 26, pages 627-638. Photos: Seth Baum, and Chimen Lakay.

Follow Scientific American on Twitter @SciAm and @SciamBlogs. Visit ScientificAmerican.com for the latest in science, health and technology news.
© 2012 ScientificAmerican.com. All rights reserved.


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Cautious reformers tipped for new China leadership
















BEIJING (Reuters) – China‘s ruling Communist Party will this month unveil its new top leadership team, expected to again be an all-male cast of politicians whose instincts are to move cautiously on reform.


Sources close to the leadership say 10 main candidates are vying for seven seats on the party’s next Politburo Standing Committee, the peak decision-making body which will steer the world’s second-largest economy for the next five years.













Only two candidates are considered certainties going into the party’s 18th congress, which starts on Thursday: leader-in-waiting Xi Jinping and his designated deputy, Li Keqiang, who are set to be installed as president and premier next March.


Of the remaining eight contenders, only one has the reputation as a political reformer and only one is a woman.


Following are short biographies of the candidates, including their reform credentials and possible portfolio responsibilities.


XI JINPING


REFORM CREDENTIALS: Considered a cautious reformer, having spent time in top positions in Fujian and Zhejiang provinces, both at the forefront of China‘s economic reforms.


Xi Jinping, 59, is China‘s vice president and President Hu Jintao’s anointed successor. He will take over as Communist Party boss at the congress and then as head of state in March.


Xi belongs to the party’s “princeling” generation, the offspring of communist revolutionaries. His father, former vice premier Xi Zhongxun, fought alongside Mao Zedong in the Chinese civil war. Xi watched his father purged and later, during the Cultural Revolution, spent years in the hardscrabble countryside before making his way to university and then to power.


Married to a famous singer, Xi has crafted a low-key and sometimes blunt political style. He has complained that officials’ speeches and writings are clogged with party jargon and has demanded more plain speaking.


Xi went to work in the poor northwest Chinese countryside as a “sent-down youth” during the chaos of the 1966-76 Cultural Revolution, and became a rural commune official. He went on to study chemical engineering at Tsinghua University in Beijing and later gained a doctorate in Marxist theory from Tsinghua.


A native of the poor, inland province of Shaanxi, Xi was promoted to governor of southeastern Fujian province in 1999 and became party boss in neighboring Zhejiang province in 2003.


In 2007, the tall, portly Xi secured the top job in China‘s commercial capital, Shanghai, when his predecessor was caught up in a huge corruption case. Later that year he was promoted to the party’s standing committee.


- – - -


LI KEQIANG


REFORM CREDENTIALS: Seen as another cautious reformer due to his relatively liberal university experiences.


Vice Premier Li Keqiang, 57, is the man tipped to be China‘s next premier, taking over from Wen Jiabao.


His ascent will mark an extraordinary rise for a man who as a youth was sent to toil in the countryside during Mao’s Cultural Revolution.


He was born in Anhui province in 1955, son of a local rural official. Li worked on a commune that was one of the first places to quietly revive private bonuses in farming in the late 1970s. By the time he left Anhui, Li was a Communist Party member and secretary of his production brigade.


He studied law at the elite Peking University, which was among the first Chinese schools to resume teaching law after the Cultural Revolution. He worked to master English and co-translated “The Due Process of Law” by Lord Denning, the famed English jurist.


In 1980, Li, then in the official student union, endorsed controversial campus elections. Party conservatives were aghast, but Li, already a prudent political player, stayed out of the controversial vote.


He climbed the party ranks and in 1983 joined the Communist Youth League’s central secretariat, headed then by Hu Jintao.


Li later served in challenging party chief posts in Liaoning, a frigid northeastern rustbelt province, and rural Henan province. He was named to the powerful nine-member standing committee in 2007.


- – - -


WANG QISHAN


REFORM CREDENTIALS: A financial reformer and problem solver with deep experience tackling tricky economic and political problems.


Wang Qishan, 64, is the most junior of four vice premiers and an ex-mayor of Beijing. But he has a keen grasp of complex economic issues and is the only likely member of the Standing Committee to have been chief executive of a corporation, leading the state-owned China Construction Bank from 1994 to 1997. As such, he may take a leading role in shaping economic policy, including trade and foreign investment.


Wang is an experienced negotiator who has led finance and trade negotiations as well as the Strategic and Economic Dialogue with the United States. He is a favorite of foreign investors and has long been seen as a problem solver, sorting out a debt crisis in Guangdong province where he was vice governor in the late 1990s and replacing the sacked Beijing mayor after a cover-up of the deadly SARS virus in 2003.


Wang is also a princeling, son-in-law of a former vice premier and ex-standing committee member, Yao Yilin. His possible portfolio could be chairman of the National People’s Congress (China’s rubber-stamp parliament), head of parliament’s advisory body, executive vice premier (responsible for economic issues) or the party’s top anti-corruption official.


- – - -


LIU YUNSHAN


REFORM CREDENTIALS: A conservative who has kept domestic media on a tight leash.


Liu Yunshan, 65, may take over the propaganda and ideology portfolio for the Standing Committee.


He has a background in media, once working as a reporter for state-run news agency Xinhua in Inner Mongolia, where he later served in party and propaganda roles before shifting to Beijing.


As minister of the party’s Propaganda Department since 2002, Liu has also sought to control China‘s Internet, which has more than 500 million users. He has been a member of the wider Politburo for two five-year terms ending this year.


Liu has not worked directly for the Communist Youth League, but is aligned to it through his lengthy career in an inland, poor province, long ties to the party’s propaganda system and close relationship with Hu Jintao.


- – - -


LI YUANCHAO


REFORM CREDENTIALS: A reformer who has courted foreign investment and studied in the United States.


Li Yuanchao, 61, oversees the appointment of senior party, government, military and state-owned enterprise officials as head of the party’s powerful organization department. On the Standing Committee, he could head the fight against corruption.


Li, whose father was a vice-mayor of Shanghai, has risen far since his parents were persecuted and he was a humble farm hand during the Cultural Revolution.


Politically astute, Li can navigate between interest groups, from Hu’s Youth League power base to the princelings.


As party chief in his native province, Jiangsu, from 2002 to 2007, Li oversaw a rapid rise in personal incomes and economic development, attracting foreign investment from global industrial leaders such as Ford, Samsung and Caterpillar.


He earned mathematics and economics degrees from two of China‘s best universities and a doctorate in law. He also spent time at Harvard University’s Kennedy School of Government in the United States.


- – - -


ZHANG DEJIANG


REFORM CREDENTIALS: A conservative trained in North Korea.


Zhang Dejiang, 65, saw his chances of promotion boosted this year when he was chosen to replace disgraced politician Bo Xilai as Chongqing party boss. He also serves as vice premier in charge of industry, though his record has been tarnished by the downfall of the railway minister last year for corruption.


Zhang is close to former president Jiang Zemin who still wields some influence. He studied economics at Kim Il-sung University in North Korea and is a native of northeast China.


On his watch as party chief of Guangdong, the southern province maintained its position as a powerhouse of China‘s economic growth, even as it struggled with energy shortages, corruption-fuelled unrest and the 2003 SARS epidemic.


- – - – -


ZHANG GAOLI


REFORM CREDENTIALS: A financial reformer with experience in more developed parts of China.


Zhang Gaoli, 65, party chief of the northern port city of Tianjin and a Politburo member since 2007, is seen as a Jiang Zemin ally but also acceptable to President Hu, who has visited Tianjin three times since 2008. Zhang is an advocate of greater foreign investment and he introduced financial reforms in a bid to turn the city into a financial center in northern China.


He was sent to clean up Tianjin, which was hit by a string of corruption scandals implicating his predecessor and the former top adviser to the city’s lawmaking body. The adviser committed suicide shortly after Zhang’s arrival.


A native of southeastern Fujian province, Zhang trained as an economist. He also served as party chief and governor of eastern Shandong province and as Guangdong vice governor.


Zhang is low-key with a down-to-earth work style, and not much is known about his specific interests and aspirations. But with his leadership experience in more economically advanced cities and provinces, including party secretary of the showcase manufacturing and export-driven city of Shenzhen, he could be named executive vice premier.


- – - – -


WANG YANG


REFORM CREDENTIALS: Seen by many in the West as a beacon of political reform.


Wang Yang, 57, is party chief of the export dependent economic hub of Guangdong province. He was not included in a list of preferred Standing Committee candidates drawn up by Xi, Hu and Hu’s predecessor, Jiang Zemin, according to sources close to the leadership, but is firmly in the running.


Born into a poor rural family in eastern Anhui province, Wang dropped out of high school and went to work in a food factory at age 17 to help support his family after his father died. These experiences may have shaped his desire for more socially inclusive policies, including his “Happy Guangdong” model of development designed to improve quality of life.


Concerned about the social impact of three decades of blistering development, he lobbied for social and political reform. However, this approach has drawn criticism from party conservatives and Wang has more recently adopted the party’s more familiar method of control and punishment to keep order.


- – - – -


YU ZHENGSHENG


REFORM CREDENTIALS: Relatively low-key but considered a cautious reformer.


Yu Zhengsheng, 67, is party boss in China‘s financial hub and most cosmopolitan city, Shanghai.


His impeccable Communist pedigree made him a rising star in the mid-1980s until his brother, an intelligence official, defected to the United States. His close ties with Deng Pufang, the eldest son of late paramount leader Deng Xiaoping, spared him the full political repercussions but he was taken off the fast track.


Yu bided his time in ministerial ranks until bouncing back, joining the Politburo in 2002. However, the princeling’s age would require him to retire in 2017 after one term.


- – - – -


LIU YANDONG


REFORM CREDENTIALS: Uncertain.


Liu Yandong, who turns 67 this month, is the only woman given a serious chance to join the Standing Committee but is considered a dark horse. She is a princeling also tied to President Hu’s Youth League faction.


If promoted, she could head up parliament’s advisory body, but her age would also force her to retire after only one term.


Her bigger challenge is that no woman has made it into the Standing Committee since 1949. Not even Jiang Qing, the widow of late Chairman Mao Zedong, made it that far.


Liu, daughter of a former vice-minister of agriculture, is currently the only woman in the 25-member Politburo, a minority in China‘s male-dominated political culture. She has been on the wider Politburo since 2007 as one of five state councilors, a rank senior to a cabinet minister but junior to a vice-premier.


(Reporting by Terril Yue Jones, Ben Blanchard, Benjamin Kang Lim and Sui-Lee Wee in Beijing. Additional reporting by Chris Ip, Grace Li, Jean Lin, Young Wang, Alice Woodhouse and Julie Zhu; Editing by Raju Gopalakrishnan and Mark Bendeich)


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Apple sells 3 million iPads over first weekend
















SAN FRANCISCO/NEW YORK (Reuters) – Apple Inc sold 3 million of its new iPads in the first three days the tablet computers were available, driving optimism for a strong holiday quarter despite intensifying competition.


Sales of the 7.9-inch iPad mini and fourth-generation 9.7-inch version, both Wi-Fi only models, were double the first-weekend sales of the Wi-Fi iPad sold in March, Apple said on Monday.













Apple did not break out numbers for the crucial iPad mini, a smaller version of the original tablet designed to spearhead its foray into a segment now dominated by Amazon.com Inc and Google Inc.


Analysts estimate that about 2.3 million of the new iPads sold over the weekend were the mini-tablets, surpassing expectations of 1 million to 1.5 million.


Wall Street, which was disappointed with Apple’s latest quarterly earnings, had been looking to the iPad mini to boost demand during the crucial year-end holiday shopping season as competition reaches a fever pitch. Microsoft Corp became the latest major entrant to the market last month with the Windows-driven Surface.


While lines for the new iPads appeared lighter than usual when they began selling at stores on Friday, the company said demand was so strong that it “practically sold out of iPad minis.”


Apple had never before introduced two different iPad models in one quarter. Raymond James analyst Tavis McCourt said that while the sales number looked good, the company would need to sell another 20 million iPads this quarter to meet his estimate.


“There’s still a lot of wood to chop in the quarter,” McCourt said.


The company said it had shipped many of the new iPads ordered before the release date, but would not send some out until later this month.


Apple had sold 3 million iPads in March, including those with cellular connections as well as Wi-Fi only models.


“We set a new launch weekend record and practically sold out of iPad minis,” Apple Chief Executive Tim Cook said in a statement. “We’re working hard to build more quickly to meet the incredible demand.”


HOLIDAY SALES CRUCIAL


Apple shares were up 1.7 percent at $ 586.50 in morning trading on Nasdaq, still down more than 16 percent from a record high set in September.


The 7.9-inch iPad mini marks Apple’s first foray into the smaller-tablet segment and is the company’s first major new device since the death of co-founder Steve Jobs last year.


Versions of iPads with both Wi-Fi and cellular connections will not ship in the United States for another few weeks. And both will hit more countries later this year.


The iPad mini takes aim at Google’s Nexus 7 and Amazon’s Kindle Fire. At stores around the world, the product’s debut drew sparser crowds than previous launches did, dampening initial optimism for sales. Still, the mini attracted hundreds of people in many locations.


Apple heads into the current quarter after refreshing almost all of its product lines, from Macintosh computers to tablets.


“We believe the iPad mini has the opportunity to surpass the sales of the regular-sized iPads over the next several years,” said Topeka Capital analyst Brian White.


(Reporting by Sayantani Ghosh in Bangalore and Sinead Carew in New York; Editing by Saumyadeb Chakrabarty and Lisa Von Ahn)


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Amgen experimental drug lowers cholesterol in mid-stage trial
















LOS ANGELES (Reuters) – Amgen Inc‘s experimental drug AMG145 reduced levels of bad cholesterol by as much as 55 percent in combination with statin drugs in patients genetically predisposed to high cholesterol, according to data from a midstage trial presented on Monday.


The new drug, given by injection every four weeks, is part of a promising new class of biotech medicines known as PCSK9 inhibitors designed to target a protein that prevents the body from removing artery blocking LDL cholesterol from the bloodstream.













Statins, such as Pfizer Inc‘s Lipitor and AstraZeneca’s Crestor, work by preventing the liver from making cholesterol.


The Phase II trial found that after 12 weeks, patients treated with a low dose of AMG145 had a 43 percent reduction in LDL, while those given a higher dose had a drop of 55 percent. Patients treated with a placebo saw a 1 percent increase in LDL cholesterol.


The trial, presented here at the annual scientific meeting of the American Heart Association, included 168 patients with heterozygous familial hypercholesterolemia, in which a defective gene inherited from one parent impairs the ability to properly metabolize LDL. The disorder is estimated to affect about one in 500 people and causes extremely high cholesterol.


The most common side effects seen in the trial were injection-site reactions, cold-like symptoms and headache.


AMG145, along with other PCSK9 inhibitors being developed by companies like Pfizer, Regeneron Pharmaceuticals Inc in partnership with Sanofi and Roche, is a man-made antibody.


(Reporting By Deena Beasley; Editing by Bernard Orr)


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France urged to cut labour costs

















France’s President Francois Hollande is under pressure to reform its flagging economy after both the IMF and a separate government-commissioned report urged him to slash employment costs.













The International Monetary Fund said France must act or risk falling further behind its European peers.


The former boss of aerospace group EADS, Louis Gallois, urged the government to improve competitiveness.


Mr Gallois wants French payroll taxes cut by 30bn euros (£24bn) in two years.


Mr Gallois was asked by President Francois Hollande to investigate what was holding France back, as part of a “competitiveness pact”, looking at why the French economy has fallen behind rivals such as Germany and suggesting reforms that could help address the gap.


France accounts for just 13% of eurozone exports, compared with 17% a year ago, and its unemployment rate stands at 10.2%, as against Germany’s 6.9%.


The report’s 22 proposals include slashing the social contributions paid by employers by 20bn euros (£16bn), as well as those paid by employees by 10bn euros.


To recoup some of these lost funds, the report suggests increasing VAT and making cuts to public spending.


Mr Gallois also suggests the creation of a set of laws to make the creation of start-up businesses easier.


Growth ‘overshadowed’


Similarly, the IMF, in its annual review of the French economy, said France should ease employment laws to make it easier to both hire and fire workers, as well as cut payroll taxes to encourage employers to hire more staff.


The IMF also suggested the government should make working hours more flexible, limit future rises in the minimum wage and reduce unemployment benefits during economic upturns to provide a greater incentive to look for work.


“[France's] growth outlook is being overshadowed by a significant loss of competitiveness,” the IMF said.


Last month, the IMF cut its growth forecasts for Europe’s second-largest economy to 0.1% this year and 0.4% in 2013, from 0.3% and 0.8% respectively.


President Hollande, whose official response to the Gallois report is due on Tuesday, insisted he would take “tough decisions”, but said his policy needed to be “holistic”.


The government has already made clear that it will not contemplate shifting more of the tax burden on to households when it has already drastically cut spending, in a bid to reduce its 2013 deficit to 3% of gross domestic product (GDP) from 4.5%.


An indication of the report’s likely reception came from Social Economy Minister Benoit Hamon.


“This report is a contribution. It’s the government that governs,” he said.


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Will Ferrell Will Do Anything to Get You to Vote in Comedic PSA [VIDEO]

























GIve you a tattoo, eat underpants and human toenails, punch himself in the face … These are just a few of the things that Will Ferrell will do to get you to vote in Tuesday’s U.S. election.


[More from Mashable: Chris Rock Is Voting for the Whitest Candidate [VIDEO]]





















In a roughly minute-long YouTube video, the comedian shares a laundry list of tasks he will perform, ranging from the mundane to the bizarre.


Viewers can apparently hold Ferrell to his promise, as he proclaims, “I’m not kidding.”


[More from Mashable: John F. Kennedy Calls on Public to Vote [VIDEO]]


He concludes the video, posted to Barack Obama’s official YouTube page, by endorsing the president.


Will you heed Ferrell’s call to action? Tell us in the comments below.


Thumbnail image courtesy of Eva Rinaldi Photography


This story originally published on Mashable here.


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What election? Sandy’s the big story on ‘SNL’

























NEW YORK (AP) — You wouldn’t have known it was the Saturday before the election on “Saturday Night Live.”


Sure, Mitt Romney, played by Jason Sudeikis, made a quick appearance on “Weekend Update,” but otherwise much of the focus was on Superstorm Sandy — and Mayor Michael Bloomberg‘s sign-language interpreter, Lydia Callis.





















The real Callis has gained some pop-culture popularity with her enthusiastic interpreting of Bloomberg’s words. She was back at the mayor’s side at Saturday’s briefing in New York and was played on “SNL” by Cecily Strong. The mayor — played by Fred Armisen — thanked Callis for bringing “pizazz” to her job.


Hosting Saturday’s show was comedian and TV star Louis C.K. He said in the monologue of New York City: “We’re still standing.”


President Barack Obama didn’t appear on the show.


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Sanofi considered moving headquarters abroad: report

























PARIS (Reuters) – Sanofi‘s management considered moving its headquarters abroad in the last few months but the plan was nixed by the drugmaker’s chairman, French weekly Le Journal du Dimanche reported on Sunday, citing sources close to the board.


First mooted in July, when the Socialist government was preparing to introduce a 75 percent tax on top earnings, the plan envisaged moving the headquarters to London or the United States, or at least relocating Chief Executive Chris Viehbacher and his closest associates abroad.





















However, Chairman Serge Weinberg vetoed the project, the newspaper said, saying that Viehbacher had not raised the issue with him.


A Sanofi spokesman denied such plans were discussed and said the company’s recent move to new corporate headquarters in Paris showed its commitment to its base in the city.


Several of the company’s top executives are foreign and spend most of their time travelling abroad.


In addition to German-Canadian Viehbacher, they include Elias Zerhouni, an Algerian-born American in charge of research and development, and Hanspeter Spek, the German-born president of global operations.


Italian Roberto Pucci, senior vice president of human resources, and Karen Linehan, Sanofi’s American-born general counsel, are also part of the executive committee.


Sanofi, which is reshuffling its French research operations at a cost of around 900 jobs, would not be the first French firm to consider moving top executives overseas.


French industrial conglomerate Schneider Electric has kept its headquarters near Paris, but its top managers, including Chief Executive Jean-Pascal Tricoire, relocated to Hong Kong last year in a move to be closer to fast-growing markets in Asia.


Industry Minister Arnaud Montebourg, who has opposed the reorganization of Sanofi’s research activities in France, was cited by the newspaper as saying he hoped the plan was just a rumor.


(Reporting by Elena Berton; Editing by Hugh Lawson)


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Apple paid only 2% tax outside US


























Apple paid less that 2% corporation tax on its profits outside the US, its filing with US regulators has shown.





















Apple paid $ 713m (£445m) in the year to 29 September on foreign pre-tax profits of $ 36.8bn (£23.0bn), a rate of 1.9%.


It is the latest company to be identified as paying low rates of overseas tax, following Starbucks, Facebook and Google in recent weeks.


It has not been suggested that any of their tax avoidance schemes are illegal.


All of the companies do pay considerable amounts of other taxes in the UK such as National Insurance and raise large sums of VAT.


Apple’s figures for foreign tax appear on page 61 of its form 10k filing with the Securities and Exchange Commission (SEC).


It had paid a rate of 2.5% the previous year.


Apple channels much of its business in Europe through a subsidiary in the Republic of Ireland, which has lower corporation tax than Britain.


But even Ireland charges 12.5%, compared with Britain’s 24%.


Many multinational companies manage to pay substantially below the official corporation tax rates by using tax havens such as Caribbean islands.


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