Hot flashes may return after ending antidepressant

NEW YORK (Reuters Health) – For about a third of women taking antidepressants to treat menopause symptoms, hot flashes and night sweats will return after discontinuing the drug, according to a new study.

“It’s important for people to understand that…the benefit of the treatment is related to the duration of the treatment,” said Dr. Hadine Joffe, lead author of the study. But that shouldn’t discourage women from trying an antidepressant if they want to, she added.

“Just because symptoms come back after you stop it doesn’t mean it didn’t make a big difference when you took it,” said Joffe, who is an associate professor of psychiatry at Harvard Medical School and director of research in the Center for Women’s Mental Health at Massachusetts General Hospital.

Escitalopram, an antidepressant sold under the brand name Lexapro, is not approved to treat menopause symptoms, but physicians may prescribe it because some – though not all – studies have found it can reduce the number and severity of hot flashes.

It has “a moderate effect,” Joffe told Reuters Health. “The drug does not eliminate hot flashes, but it can make “a very meaningful improvement in somebody’s life.”

Antidepressants of the same type as Lexapro, called selective serotonin reuptake inhibitors (SSRIs), are also used to treat menopause symptoms.

Joffe said there have not been enough studies to determine just how long women should take an antidepressant to treat hot flashes, nor whether the symptoms return once they stop the treatment.

To address the second question, she and her colleagues asked 200 women to take 10 or 20 milligrams a day of Lexapro for eight weeks.

The team’s final analysis included 76 women who showed at least a 20 percent improvement on the drug – for instance, dropping from 10 hot flashes a day down to eight or fewer.

After the two-month treatment period, the women stopped taking the pills and the researchers tracked their symptoms for another three weeks. The team was also careful to screen for withdrawal symptoms from the drug itself.

Menopause symptoms returned for about a third of the women who had seen an improvement on the drugs. Results were similar whether the women had reported experiencing less severe symptoms while on the drug or had said they felt less bothered by their symptoms during treatment.

Among 49 women who said they had benefitted on all three symptom measures – number, severity and bothersomeness – 44 percent experienced a relapse within three weeks of discontinuing the drug.

For most of those women, symptoms rebounded to about the same levels as before the treatment.

Among the women who didn’t relapse, symptoms dropped from about 9.5 a day before treatment to 4.4 per day three weeks after stopping.

Joffe said it’s impossible to say whether this group would experience a greater return of symptoms later on, or would continue to see a reduction.

“We only looked within three weeks of stopping the medication,” she said. “We don’t know (what would happen) if we studied them for six weeks or six months.”

Patients who experienced insomnia before taking the antidepressant or who didn’t find a large benefit from the drug were more likely to relapse than other women.

Some women also experienced withdrawal symptoms characteristic of going off an antidepressant, including sweating and dizziness.

About 46 percent of the women reported that they felt at least two withdrawal symptoms.

Joffe and some of her colleagues have relationships with pharmaceutical companies, two of them with Lexapro’s maker, Forest Laboratories.

She pointed out that while Forest Labs provided the pills, the company had no participation in the study, which was funded by a variety of government grants.

The company declined to comment on the study because it was not involved.

Warning labels on antidepressants do not include information about treatment for menopause symptoms because they have not been approved for that use by the Food and Drug Administration.

Dr. Judith Ockene, a professor at the University of Massachusetts Medical School, who did not participate in the research, said it’s the onus of physicians, the media and patients themselves to understand the pros and cons of taking the medication.

“I think women should be educated about the likelihood of (symptom) relapse when they discontinue SSRIs, even if they perceive benefits in the short term,” she said.

Ockene pointed out that some women experience a rebounding of symptoms after they stop taking hormone replacement therapy too.

“We say if women are taking hormones to help them with menopausal symptoms, then they need to be mindful of the fact that when they stop them they may have a return of their symptoms,” Ockene told Reuters Health.

She said the same should be communicated to women thinking of taking an antidepressant and incorporated into their decision-making about using the medications.

SOURCE: http://bit.ly/X4ZmBL Menopause, online October 22, 2012.

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Myanmar cracks down on mine protest; dozens hurt

MONYWA, Myanmar (AP) — Security forces used water cannons and other riot gear Thursday to clear protesters from a copper mine in in northwestern Myanmar, wounding villagers and Buddhist monks just hours before opposition leader Aung San Suu Kyi was to visit the area to hear their grievances.

The crackdown at the Letpadaung mine near the town of Monywa risks becoming a public relations and political fiasco for the reformist government of President Thein Sein, which has been touting its transition to democracy after almost five decades of repressive military rule.

The environmental and social damage allegedly produced by the mine has become a popular cause in activist circles, but was not yet a matter of broad public concern. However, hurting monks — as admired for their social activism as they are revered for their spiritual beliefs — is sure to antagonize many ordinary people, especially as Suu Kyi’s visit highlights the events.

“This is unacceptable,” said Ottama Thara, a 25-year-old monk who was at the protest. “This kind of violence should not happen under a government that says it is committed to democratic reforms.”

According to a nurse at a Monywa hospital, 27 monks and one other person were admitted with burns caused by some sort of projectile that released sparks or embers. Two of the monks with serious injuries were sent for treatment in Mandalay, Myanmar’s second biggest city, a 2 ½ hour drive away. Other evicted protesters gathered at a Buddhist temple about 5 kilometers (3 miles) from the mine’s gates.

Lending further sympathy to the protesters’ cause is whom they are fighting against. The mining operation is a joint venture between a Chinese company and a holding company controlled by Myanmar’s military. Most people remain suspicious of the military, while China is widely seen as having propped up army rule for years, in addition to being an aggressive investor exploiting the country’s many natural resources.

Government officials had publicly stated that the protest risked scaring off foreign investment that is key to building the economy after decades of neglect.

State television had broadcast an announcement Tuesday night that ordered protesters to cease their occupation of the mine by midnight or face legal action. It said operations at the mine had been halted since Nov. 18, after protesters occupied the area.

Some villagers among a claimed 1,000 protesters left the six encampments they had at the mine after the order was issued. But others stayed through Wednesday, including about 100 monks.

Police moved in to disperse them early Thursday.

“Around 2:30 a.m. police announced they would give us five minutes to leave,” said protester Aung Myint Htway, a peanut farmer whose face and body were covered with black patches of burned skin. He said police fired water cannons first and then shot what he and others called flare guns.

“They fired black balls that exploded into fire sparks. They shot about six times. People ran away and they followed us,” he said, still writhing hours later from pain. “It’s very hot.”

Photos of the wounded monks showed they had sustained serious burns on parts of their bodies. It was unclear what sort of weapon caused them.

The protest is the latest major example of increased activism by citizens since the elected government took over last year. Political and economic liberalization under Thein Sein has won praise from Western governments, which have eased sanctions imposed on the previous military government because of its poor record on human and civil rights. However, the military still retains major influence over the government, and some critics fear that democratic gains could easily be rolled back.

In Myanmar’s main city of Yangon, six anti-mine activists who staged a small protest were detained Monday and Tuesday, said one of their colleagues, who asked not to be identified because he did not want to attract attention from the authorities.

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Italian tax police probe Google Italy again

ROME (Reuters) – Italian police launched a new tax probe into Google Italy this week after earlier investigations found the group had failed to declare income and still owed sales tax, an economy ministry document showed on Wednesday.

The earlier probe, which was launched by Italian financial police in 2007, found that Google had developed a system to transfer profits from its Italian operations to Ireland so it could benefit from a more favorable tax regime.

The investigation is the Internet search giant’s latest entanglement with European tax authorities, following problems in France and Britain over its Irish strategy.

In Italy, investigations of the years 2002-2006 found that Google had failed to declare at least 240 million euros ($ 310 million) of income to authorities and owed more than 96 million euros in sales tax, according to the ministry’s response to questions in parliament.

It said police had launched a new probe on Monday to check the company was meeting its fiscal obligations in Italy.

Google said in a statement that it complies with tax law in every country in which it operates.

“We are confident we comply with Italian law,” a spokeswoman said, adding the firm would cooperate with authorities and answer any questions for the investigation.

Italian officials have stepped up tax surveillance and collection efforts in recent months as part of government efforts to bring Italy’s huge public debt under control.

Police have also been assessing the practices of other multinational online businesses who are managing to shift profits made in Italy into countries where they can pay less tax, the ministry said.

($ 1=0.7746 euros)

(Reporting By Danilo Masoni, Giuseppe Fonte and Catherine Hornby; Editing by Mike Nesbit)

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Global High Fructose Corn Syrup Use May Be Fueling Diabetes Increase

Image courtesy of iStockphoto/TheCrimsonMonkey

It doesn’t matter where you look: the U.S., Mexico, Malaysia or Portugal, the more high fructose corn syrup consumption, on average, the more diabetes. A new study of 43 countries in Global Public Health, published online November 27, found that adult type-2 diabetes is 20 percent higher in countries that consume large quantities of high fructose corn syrup. “The study adds to a growing body of scientific literature that indicates HFCS consumption may result in negative health consequences distinct from and more deleterious than natural sugar,” Michael Goran, of the University of Southern California Department of Preventive Medicine and co-author of the new study, said in a prepared statement. Countries in which per person annual high fructose corn syrup (HFCS) consumption was less than 0.5 kg had similar BMIs, daily calorie intake and total sugar intake as did countries in which HFCS was higher. The big difference in these two groups of countries was diabetes prevalence. The link between HFCS and poor health outcomes–such as obesity or diabetes-has often been speculated, but it has been difficult to prove. The availability of the cheaper-than-sugar sweeteners starting in the U.S. in the 1970s appears to have helped boost the number of overall calories people imbibe. In the U.S. today, for example, high fructose corn syrup is in everything from sodas to ketchup. In fact, we each consume, on average, some 24.8 kilograms of this processed corn sweetener every year. With the extra calories, weight gain has quickened, leading to more obesity, one of the strongest risk factors for type-2 diabetes. HFCS may also pose a greater risk for diabetes greater than pure sugar alone. Instead of a composition evenly divided between fructose and glucose like table sugar, HFCS contains as much as 30 percent more fructose. (The exact quantities are unknown because manufacturers are not required to disclose the amount on food and beverage packages.) Glucose is metabolized quickly and used as energy or retained as fat. But fructose processing is more complex. It is broken down primarily in the liver and seems to induce less leptin production (a hormone that signals fullness to the body) and less insulin (which is why sweeteners composed primarily of fructose are sometimes recommended for people who already have diabetes). Some studies have also found fructose consumption increases the types of fats that are linked to insulin resistance, a hallmark of diabetes. These scattered findings suggest that “our metabolism has not evolved sufficiently to be able to process the fructose from high fructose corn syrup in the quantities that some people are consuming it,” Stanly Ulijaszek, of the University of Oxford and study co-author, said in a prepared statement. Some illuminating international differences emerged during the course of the study. For example, the European Union imposes production quotas for HFCS for member countries. Those countries, such as Sweden, that do not use the sweetener in their own food supply can export it to countries, such as Hungary, that are willing to buy more for residents. This distribution imbalance allowed the researchers to compare countries that were similar in other respects (BMI, gross national product, etc.) but different in HFCS consumption. While the U.S. is the largest producer–and consumer–of HFCS and has been for decades (thanks in large part to farm subsidies), other countries are just beginning to experience high amounts of HFCS in the food system. Mexico, for example, long limited imports of HFCS to protect their own sugar market. In 2008, however, those barriers were removed, and for the past few years, HFCS has been flooding in from the U.S. The authors of the study argue that with the new findings, perhaps some of these policies should be revisited. Further research into the mechanisms for the possible link between HFCS consumption and diabetes risk remains to be done. But, “if HFCS is a risk factor for diabetes–one of the world’s most serious chronic diseases–then we need to rewrite national dietary guidelines and review agricultural trade policies,” Tim Lobstein, director of policy at the International Association for the Study of Obesity, said in a prepared statement.

Follow Scientific American on Twitter @SciAm and @SciamBlogs. Visit ScientificAmerican.com for the latest in science, health and technology news.
© 2012 ScientificAmerican.com. All rights reserved.

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New home sales stagnant, cast shadow on housing

WASHINGTON (Reuters) – New U.S. single-family home sales fell slightly in October and the prior month’s pace of sales was revised sharply lower, casting a faint shadow over one of the brighter spots in the U.S. economy.

The Commerce Department said on Wednesday sales dropped 0.3 percent last month to a 368,000-unit annual rate, while September’s sales pace was revised to 369,000 from 389,000.

The housing sector has been a point of relative strength this year in an economy beset by flagging business confidence and cooling demand from abroad.

A report last week showed a surprisingly sharp gain in home resales in October, while data this week showed prices for single-family homes have risen continuously since February.

Economists expect home construction to add to economic growth this year for the time since 2005.

Wednesday’s data did not change the view that housing is still in recovery mode, although the pace of new home sales in October was below the level of May, suggesting little upward momentum.

“It’s just that progress will be slow,” said Yelena Shulyatyeva, an economist at BNP Paribas in New York.

U.S. homebuilder stocks fell, even as broad market indexes rose slightly.

While weakness in business spending has been restraining growth, most recent data has suggested housing is gaining momentum. Consumer confidence has also been more bullish.

Wednesday’s report showed the median sales price for a new home in October was 5.7 percent higher than a year earlier, but the pace of year-over-year price gains slowed for a second straight month.

Some analysts suggested the decline in sales in October might be partially due to a mammoth storm that slammed into the U.S. East Coast at the end of October. New sales plunged 32.3 percent in the Northeast, which bore the brunt of the storm.

“Some of this could potentially be Hurricane Sandy,” said Megan McGrath, an analyst at MKM Partners in Stamford, Connecticut.

However, the Commerce Department said the storm did not affect data collection at all and its impact on the pace of sales was likely “minimal.”

Economists polled by Reuters had forecast sales rising to a 390,000-unit rate last month from September’s previously reported 389,000-unit rate.

To provide support for the housing market, the Federal Reserve has kept interest rates at rock-bottom levels since 2008. In September, it launched an open-ended program to buy mortgage-backed securities, driving mortgage rates to record lows.

In a separate report, data from the Mortgage Bankers Association showed an index for home purchase loans, a leading indicator of home sales, rose 2.6 percent last week to its highest level of the year.

(Additional reporting by Gabriel Debenedetti in New York; Editing by Andrea Ricci)

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Google Breaks All Android App Reviews, Threatens Android Fans’ Safety

“A Google User” is now the number one Android game and app reviewer on Google Play, Android’s version of Apple’s App Store. That’s because every single one of the millions of existing reviews, possibly including yours, has had its author replaced with this nameless, faceless person.

Screenshots taken by Jeremiah Rice of the Android Police blog show this prolific (but completely generic) author has taken over the Google Play store. Meanwhile, if you visit the store on your Android smartphone or tablet you won’t see a name attached to most reviews at all; just the review’s title, and the device that the game or app was run on.

Believe it or not, this is all intentional. It’s the start of a new Google policy … one which may threaten some Android fans’ safety or privacy.

​Google+, whether you like it or not

Google now requires you to have a Google+ (pronounced “Google Plus”) account in order to leave reviews on Google Play, the Chrome Web Store, and Google Maps. No reason for the switchover is given in the pop-up which explains this; you simply click “Continue” if you want your reviews tied to your Google+ account, and if you don’t want them linked you don’t write them at all. If you don’t have a Google+ account, you have to sign up for one before you can write a review.

​Why Google is Plus-ifying everything

Google’s success as a company is determined by how many ads it sells. Google’s share of the ad market is being eaten into by Facebook, which has essentially “walled off” a huge part of people’s day-to-day lives in a place Google can’t index or sell any ads on. For better or for worse, Google’s execs feel that what they need to do to compete is copy Facebook, in the form of Google+.

Why? Because if everyone is “Plusing” things instead of “Liking” them, and if everything people do shows up on Google+ instead of Facebook, then now Google (instead of Facebook) knows what you’re doing online and where you’re doing it — and that gives it a much better position from which to display and sell ads.

​Why this is a problem for many

Besides the obvious privacy concerns (although Google offers limited tools to manage how much it tracks you), Google+’s “real names” policy is dangerous to anyone whose safety is jeopardized by attaching their given name to their online activities. This includes women who are victims of stalking, minors who are victims of abuse, transgender persons in transition, and dissidents in repressive political or religious regimes. By requiring a Google+ account to use more and more of its services, Google is forcing these people to choose between excluding themselves and running the risk of having ​all​ of their Google services terminated for a “real name” policy violation, including their personal Gmail accounts.

Google+ policy allows for pseudonymous accounts, if you’re widely known by that pseudonym online. Everyone’s Google+ page, however, has a button to report what anyone feels is a suspicious name, which puts marginalized persons like those listed above at the mercy of every “troll” who comes by.

Jared Spurbeck is an open-source software enthusiast, who uses an Android phone and an Ubuntu laptop PC. He has been writing about technology and electronics since 2008.
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Disney Channel to debut ‘Sofia the First’ Jan. 11

NEW YORK (AP) — Disney says its animated children‘s series “Sofia the First” will premiere Jan. 11 on the Disney Channel and Disney Junior networks.

Created for kids ages 2 to 7, “Sofia the First” is about a young girl who becomes a princess and learns that honesty, loyalty and compassion are what makes a person royal.

Sofia is voiced by “Modern Family” actress Ariel Winter, and her mother is played by “Grey’s Anatomy” star Sara Ramirez.

Last week’s premiere of the “Sofia the First” animated movie drew a total audience of more than 5 million viewers. It was the year’s top-rated cable TV telecast among kids ages 2 to 5.

In the series’ debut episode, Sofia strives to become the first princess to earn a spot on her school’s flying derby team.

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CDC: HIV spread high in young gay males

NEW YORK (AP) — Health officials say 1 in 5 new HIV infections occur in a tiny segment of the population — young men who are gay or bisexual.

The government on Tuesday released new numbers that spotlight how the spread of the AIDS virus is heavily concentrated in young males who have sex with other males. Only about a quarter of new infections in the 13-to-24 age group are from injecting drugs or heterosexual sex.

The Centers for Disease Control and Prevention said blacks represented more than half of new infections in youths. The estimates are based on 2010 figures.

Overall, new U.S. HIV infections have held steady at around 50,000 annually. About 12,000 are in teens and young adults, and most youth with HIV haven’t been tested.

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Online:

CDC report: http://www.cdc.gov/vitalsigns

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From Wartime Technology Comes Hurricane Relief

A parking lot on Rockaway Beach Boulevard, in the heart of the Hurricane Sandy-ravaged New York coastline, has been serving as the base of operations for Team Rubicon, a volunteer organization staffed by military veterans who show up when disasters strike. The lot has many of the things you’d expect to see at a disaster-recovery site: stacks of hand tools, portable toilets, palettes of food, and water. What’s most interesting is the matte-green school bus parked in back.

Courtesy Team RubiconThat bus is a mobile command post, a place from which dispatchers can direct teams of volunteers to various addresses to assess damage, provide assistance, or call for supplies. To make that process more efficient, Team Rubicon employs software that is more commonly used on the battlefield but is now helping aid workers as they move from house to house.

The software comes from Palantir, a tech company in Silicon Valley that makes software used by the military, intelligence. and law-enforcement communities. Palantir’s software, which works on both laptops in the bus and on volunteers’ smartphones, allows dispatchers to see the volunteers’ locations, via their phones’ GPS function, along with the whereabouts of houses that need assistance. Aid workers can call up notes associated with a particular property and can add their own comments. They can also upload geo-tagged photos in case the address information is faulty and visual confirmation is more reliable.

Members of Team Rubicon and Palantir first met in August at the Classy Awards, a philanthropic awards ceremony held in San Diego. “The initial intent was to use Palantir to better understand their volunteer base,” says Jason Payne, who heads up Palantir’s “philanthropy engineering” team. The first plan was to more accurately match volunteers’ skills to needed tasks, but Sandy’s arrival forced a pivot to the more immediate concerns of recovery management. “It became an alpha or beta run to see how the platform could be applied to their activities on the ground,” Payne says.

Palantir’s software is designed to deal with large, disparate data sets, which can be useful in peacetime, as well as during conflicts. If you want to determine where to send aid, Payne explains, you would benefit by combining several layers of information: the status of neighborhood pharmacies and gas stations, demographic and census data, poverty rates, and other information. In the future, Payne says, such use of Palantir’s system could result in more accurate targeting of resources.

Team Rubicon began its efforts in the area on Oct. 29, and it plans to remain there until Dec. 3, at which point the group will hand over operations to longer-term recovery organizations. Its success with Palantir—the group has successfully managed more than 10,000 volunteers in the Rockaways—means that the software will likely be expanded to other aid groups. Payne mentions that such organizations as AmeriCorps, AmeriCares, and Points of Light have expressed interest in the platform.

Team Rubicon also plans to use the software again to make future relief campaigns faster and more efficient. “The Palantir software acts as a force-multiplier,” says Ford Sypher, a regional director of Team Rubicon who served as an Army Ranger in Iraq and Afghanistan. The software addresses a common problem in dispatching crews for disaster relief: lack of real-time communication. “You’d send people out to check a house, and you had no idea where they were or what they needed until they came back,” says Brendan Kraft, a volunteer who was an Army public health technician. “Now we can all share information as it comes in.”

“Before we had this,” Kraft adds, gesturing toward the satellite map imagery, overlaid with data points, “we had a pad and a pen.”

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Mexican beauty queen killed in shootout

CULIACAN, Mexico (AP) — A 20-year-old state beauty queen died in a gun battle between soldiers and the alleged gang of drug traffickers she was traveling with in a scene befitting the hit movie “Miss Bala,” or “Miss Bullet,” about Mexico’s not uncommon ties between narcos and beautiful pageant contestants.

The body of Maria Susana Flores Gamez was found Saturday lying near an assault rifle on a rural road in a mountainous area of the drug-plagued state of Sinaloa, the chief state prosecutor said Monday. It was unclear if she had used the weapon.

“She was with the gang of criminals, but we cannot say whether she participated in the shootout,” state prosecutor Marco Antonio Higuera said. “That’s what we’re going to have to investigate.”

The slender, 5-foot-7-inch brunette was voted the 2012 Woman of Sinaloa in a beauty pageant in February. In June, the model competed with other seven contestants for the more prestigious state beauty contest, Our Beauty Sinaloa, but didn’t win. The Our Beauty state winners compete for the Miss Mexico title, whose holder represents the country in the international Miss Universe.

Higuera said Flores Gamez was traveling in one of the vehicles that engaged soldiers in an hours-long chase and running gun battle on Saturday near her native city of Guamuchil in the state of Sinaloa, home to Mexico’s most powerful drug cartel. Higuera said two other members of the drug gang were killed and four were detained.

The shootout began when the gunmen opened fire on a Mexican army patrol. Soldiers gave chase and cornered the gang at a safe house in the town of Mocorito. The other men escaped, and the gunbattle continued along a nearby roadway, where the gang’s vehicles were eventually stopped. Six vehicles, drugs and weapons were seized following the confrontation.

It was at least the third instance in which a beauty queen or pageant contestants have been linked to Mexico’s violent drug gangs, a theme so common it was the subject of a critically acclaimed 2011 movie.

In “Miss Bala,” Mexico’s official submission to the Best Foreign Language Film category of this year’s Academy Awards, a young woman competing for Miss Baja California becomes an unwilling participant in a drug-running ring, finally getting arrested for deeds she was forced into performing.

In real life, former Miss Sinaloa Laura Zuniga was stripped of her 2008 crown in the Hispanoamerican Queen pageant after she was detained on suspicion of drug and weapons violations. She was later released without charges.

Zuniga was detained in western Mexico in late 2010 along with seven men, some of them suspected drug traffickers. Authorities found a large stash of weapons, ammunition and $ 53,300 with them inside a vehicle.

In 2011, a Colombian former model and pageant contestant was detained along with Jose Jorge Balderas, an accused drug trafficker and suspect in the 2010 bar shooting of Salvador Cabanas, a former star for Paraguay‘s national football team and Mexico’s Club America. She was also later released.

Higuera said Flores Gamez’s body has been turned over to relatives for burial.

“This is a sad situation,” Higuera told a local radio station. She had been enrolled in media courses at a local university, and had been modeling and in pageants since at least 2009.

Javier Valdez, the author of a 2009 book about narco ties to beauty pageants entitled “Miss Narco,” said “this is a recurrent story.”

“There is a relationship, sometimes pleasant and sometimes tragic, between organized crime and the beauty queens, the pageants, the beauty industry itself,” Valdez said.

“It is a question of privilege, power, money, but also a question of need,” said Valdez. “For a lot of these young women, it is easy to get involved with organized crime, in a country that doesn’t offer many opportunities for young people.”

Sometimes drug traffickers seek out beauty queens, but sometimes the models themselves look for narco boyfriends, Valdez said.

“I once wrote about a girl I knew of who was desperate to get a narco boyfriend,” he said. “She practically took out a classified ad saying ‘Looking for a Narco’.”

The stories seldom end well. In the best of cases, a beautiful woman with a tear-stained face is marched before the press in handcuffs. In the worst of cases, they simply disappear.

“They are disposable objects, the lowest link in the chain of criminal organizations, the young men recruited as gunmen and the pretty young women who are tossed away in two or three years, or are turned into police or killed,” Valdez said.

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Associated Press Writer E. Eduardo Castillo contributed to this report

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